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20210602_IEEE_OJEMB_S_WAKEBE_A New Method of Measuring Retinal Vessel Diameters.pdf (682.47 kB)
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A New Method of Measuring Retinal Vessel Diameters from Fundus Photographs Based on Retinal Structure and Light Reflection

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posted on 07.10.2021, 02:16 authored by Satoshi WakebeSatoshi Wakebe, Kotaro Yamasue, Hidetoshi Itoh

We propose a new method and software for measuring blood vessel diameters from fundus photographs. In this method the edge of the blood vessel is the two minimum points in the luminance profile and diameter is distance between minimum points. We noticed the relation between W-shape of luminance profile at blood vessel transversal line and cylindrical shape, and analyzed the validity of this method using the diffuse reflection model of a cylinder shape based on the optics. The simulation image by the diffuse reflection model of the cylinder was similar to that of the blood vessel images. A newly developed software using the minimum points can measure repeated measurement in a series of photographs at the same point of the same person. The data of the repeated measurement of each person showed stability, and the coefficient of variation showed no affection of different diameter and arteriovenous distinction. Hence, we believe that the minimum points are valid as blood vessel edges. The software that measures these blood vessel edges has an extremely simple measurement procedure, possesses few errors, and is easy to automate. This method is relevant because the central reflex, which has not been utilized previously, optically represents the cylindrical three-dimensional structure of blood vessels.

Funding

This work was supported by the Kanagawa Public Health Association under 2015 Grant.

History

Email Address of Submitting Author

wakebes7@gmail.com

ORCID of Submitting Author

0000-0002-1049-3844

Submitting Author's Institution

Oimachi Clinic, and the Department of Ophthalmology and Visual Science, Yokohama City University

Submitting Author's Country

Japan

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