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A Real-time Breast Hyperthermia Monitoring Scheme Based on Processing of Microwave Scattering Parameters with Deep Learning

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preprint
posted on 05.01.2022, 21:09 by Tuba YilmazTuba Yilmaz, Mehmet Nuri Akinci, Enes Girgin, Hulusi Önal
This study proposes a new method based on deep learning to determine whether the temperature values ​​are at an appropriate level during the use of microwave hyperthermia method in the treatment of breast cancer. To implement our method, we utilize the temperature dependent dielectric properties of biological tissues to generate the heating scenarios that simulates the thermal behavior of biological tissue during the breast cancer hyperthermia treatment. Using the temperature-dependent dielectric properties we designated corresponding temperature thresholds, next, we labeled the malignant tumor region and the healthy tissue region in accordance with the pre-determined thresholds. In addition, scattering problems are solved based on treatment (hot or heated) and pre-treatment (cool) scenarios. Using the difference between hot and cool states, we train, test, and validate the CNN. Our main purpose in the project is to determine whether the tissue is heated in the desired temperature region using only the single frequency differential scattered electric field data.

Funding

The Scientific and Technological Research Council of Turkey under grant agreement 118S074.

History

Email Address of Submitting Author

girgin15@itu.edu.tr

ORCID of Submitting Author

0000-0002-1337-4816

Submitting Author's Institution

Istanbul Technical University

Submitting Author's Country

Turkey