Classification of cancer pathology reports: a large-scale comparative study
preprintposted on 2020-06-29, 17:45 authored by Stefano MartinaStefano Martina, Leonardo Ventura, Paolo Frasconi
We report about the application of state-of-the-art deep learning techniques to the automatic and interpretable assignment of ICD-O3 topography and morphology codes to free-text cancer reports. We present results on a large dataset (more than 80 000 labeled and 1 500 000 unlabeled anonymized reports written in Italian and collected from hospitals in Tuscany over more than a decade) and with a large number of classes (134 morphological classes and 61 topographical classes) for which we obtained the approval from the institutional ethics committee (CEAV 14081 oss 27/11/2018). We compare alternative architectures in terms of prediction accuracy and interpretability and show that our best model achieves a multiclass accuracy of 90.3% on topography site assignment and 84.8% on morphology type assignment. We found that in this context hierarchical models are not better than flat models and that an element-wise maximum aggregator is slightly better than attentive models on site classification. Moreover, the maximum aggregator offers a way to interpret the classification process.
Italian Ministry of Education, University, and Research, Grant 2017TWNMH2.
Email Address of Submitting Authorstefano.firstname.lastname@example.org
ORCID of Submitting Author0000-0001-6024-1752
Submitting Author's InstitutionUniversity of Florence
Submitting Author's Country