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Dual Ionic Transport Using Calcium and Sodium Signalling for Molecular Communication Systems

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posted on 2023-05-31, 05:13 authored by Carlos Danilo miranda regis, Italo Santos, Pedro Ivo Guimaraes, Emanuel thiago, Michael BarrosMichael Barros

Astrocytes have the ability to modulate neuronal communication by regulating various levels of ionic concentrations. The development of models for molecular communication ought to investigate the utilisation of various ionic transportation mechanisms, with the aim of enhancing performance and biocompatibility, thereby facilitating co-existence within cellular tissues. In this study, we suggest the utilisation of both Ca$^{2+}$ and Na$^{+}$ ions to investigate the non-linearities of propagation in cellular tissues for MC. In this study, we also investigated the impact of various ionic transport mechanisms, including the sodium-calcium exchanger, sodium-potassium pump, and calcium pump, to assess their impact on the intracellular propagation of Ca$^{2+}$. We analysed four metrics, namely channel capacity, bit error rate (BER), communication gain, and signal-to-noise ratio, to evaluate the effects of these structures.


This work was financial supported in part by Fundação de Amaparo à Pesquisa do Estado da Paraíba (FAPESQ-PB), under Grant notice 07/21.


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  • Brazil