TechRxiv
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Modeling vibrations of a tiled Talbot-Lau interferometer on a clinical CT system

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posted on 2022-09-02, 19:11 authored by Clemens SchmidClemens Schmid, Manuel ViermetzManuel Viermetz, Nikolai Gustschin, Wolfgang Noichl, Jakob Haeusele, Tobias Lasser, Thomas Koehler, Franz Pfeiffer

X-ray computed tomography (CT) is an invaluable imaging technique for non-invasive medical diagnosis. However, for soft tissue in the human body the difference in attenuation is inherently small. Grating-based X-ray phase-contrast is a relatively novel imaging method which detects additional interaction mechanisms between photons and matter, namely refraction and small-angle scattering, to generate additional images with different contrast. The experimental setup involves a Talbot-Lau interferometer whose susceptibility to mechanical vibrations hindered acquisition schemes suitable for clinical routine in the past. We present a processing pipeline to identify spatially and temporally variable fluctuations occurring in an interferometer installed on a continuously rotating clinical CT gantry. The correlations of the vibrations in the modular grating setup are exploited to identify a small number of relevant fluctuation modes, allowing for a sample reconstruction free of vibration artifacts.

Funding

Respiratory Disease Screening with Dark-Field Computed Tomography

European Research Council

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History

Email Address of Submitting Author

clemens.schmid@tum.de

ORCID of Submitting Author

0000-0002-1017-2581

Submitting Author's Institution

Technical University of Munich

Submitting Author's Country

  • Germany