Samit Chakrabarty


Leeds, UK

Samit Chakrabarty has been studying the role of spinal circuits in execution of motor tasks, their modulation by peripheral sensory and descending inputs from the brain, focussing on the plastic changes that the system undertakes during development or disease. After receiving his BSc in Zoology, Biochemistry from St Xavier’s College, Mumbai he pursued a PhD in Neurophysiology of the mammalian spinal cord at the University of Cambridge, UK. This was then followed by postdoctoral training at Columbia University, NYC and University of Manitoba, Winnipeg. He has since moved to University of Leeds as an academic researcher and is active in the field of sensory and motor control, rehabilitation, and use of technology to both study and better the lives of those with maladies affecting sensory and motor function.


  • A novel simplistic fabrication technique for cranial epidural electrodes for chronic recording and stimulation in rats
  • Peripheral nerve bionic interface: a review of electrodes
  • A survey on foot drop and functional electrical stimulation
  • A Neural Circuit Model of Proprioceptive Feedback from Muscles Recruited during an Isometric Knee Extension
  • Caudal-rostral progression of alpha motoneurone degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis
  • Toward a Closed Loop, Integrated Biocompatible Biopolymer Wound Dressing Patch for Detection and Prevention of Chronic Wound Infections
  • Guest Editorial introduction to the Focused section on wearable sensors, actuators, and robots for rehabilitation
  • Human Comfortability: Integrating Ergonomics and Muscular-Informed Metrics for Manipulability Analysis During Human-Robot Collaboration
  • C-bouton components on rat extensor digitorum longus motoneurons are resistant to chronic functional overload
  • FAST: An extension of the Wavelet Synchrosqueezed Transform
  • Activity-Based Therapies for Repair of the Corticospinal System Injured during Development
  • Pathophysiological mechanisms of impaired limb use and repair strategies for motor systems after unilateral injury of the developing brain
  • Convection enhanced drug delivery of BDNF through a microcannula in a rodent model to strengthen connectivity of a peripheral motor nerve bridge model to bypass spinal cord injury
  • Selective corticospinal tract injury in the rat induces primary afferent fiber sprouting in the spinal cord and hyperreflexia
  • Using motor behavior during an early critical period to restore skilled limb movement after damage to the corticospinal system during development
  • Modeling the Organization of Spinal Cord Neural Circuits Controlling Two-Joint Muscles
  • Descending Systems Direct Development of Key Spinal Motor Circuits
  • Simultaneous Assessment of Homonymous and Heteronymous Monosynaptic Reflex Excitability in the Adult Rat
  • Investigation of implantable antennas for exploratory neuroscience studies
  • A review of cerebral palsy - aetiology, current understanding and treatment: A call for action
  • Postnatal refinement of proprioceptive afferents in the cat cervical spinal cord
  • Harnessing activity-dependent plasticity to repair the damaged corticospinal tract in an animal model of cerebral palsy
  • Co-development of proprioceptive afferents and the corticospinal tract within the cervical spinal cord
  • Postnatal development of a segmental switch enables corticospinal tract transmission to spinal forelimb motor circuits
  • Harnessing activity-dependent plasticity in the developing corticospinal system to restore motor function after perinatal brain injury
  • Excitability of primary afferent terminations is altered after CST lesion
  • Upregulation of spinal cholinergic markers and optimal timing of constraint-induced movement therapy in a cat model of hemiplegic cerebral palsy
  • Corticospinal Development
  • Corticospinal tract injury induces primary afferent plasticity in the spinal cord
  • Delayed motor skill training restores corticospinal tract connectivity in a cat model of hemiplegic cerebral palsy
  • Activity-Dependent Codevelopment of the Corticospinal System and Target Interneurons in the Cervical Spinal Cord
  • Presynaptic control of transmission through group II muscle afferents in the midlumbar and sacral segments of the spinal cord is independent of corticospinal control
  • Activity-Dependent Plasticity Improves M1 Motor Representation and Corticospinal Tract Connectivity
  • Corticospinal Development
  • Segmental actions of the developing corticospinal tract are suppressed by muscle afferents in young animals but facilitated in older animals
  • Behavioral approaches restore corticospinal tract connectivity and function in a cat model of hemiplegic cerebral palsy
  • Changing efficacy of transmission from the corticospinal tract to spinal forelimb motor circuits during postnatal development in the cat
  • Monitoring regenrating connections with indwelling spinal cord electrodes in a spinal Motor bridge in the cat
  • Axon outgrowth from the corticospinal tract is promoted by and directed to spinal motor bridge neurons to bypass SCI
  • Early postnatal co-development of corticospinal and proprioceptive circuits in the spinal cord
  • Regenerating motor bridge axons refine connections and synapse on lumbar motoneurons to bypass chronic spinal cord injury
  • Electrical Stimulation of Spared Corticospinal Axons Augments Connections with Ipsilateral Spinal Motor Circuits after Injury
  • Motor But Not Sensory Representation in Motor Cortex Depends on Postsynaptic Activity During Development and in Maturity
  • Activity- and use-dependent plasticity of the developing corticospinal system☆
  • Effects of activity blockade on development of CST monosynaptic connections
  • Electrical stimulation of spared corticospinal axons strengthens connections with and induces outgrowth to spinal motor circuits after injury
  • How a bipartite CPG can control the activity of bifunctional motoneurons: a modeling study with insights from deletions during fictive locomotion
  • Intracellular recording from identified lumbar motoneurones of the adult mouse recorded in vivo
  • Evidence against a common excitatory drive to motoneurons innervating bifunctional and single joint muscles during fictive locomotion in cats
  • Glycinergic inhibition of locomotor-related group I disynaptic excitation in cat hindlimb motoneurons
  • Evoked Excitability Changes at the Terminals of Midlumbar Premotor Interneurons in the Cat Spinal Cord
  • Postnatal Development of the Motor Representation in Primary Motor Cortex
  • Paired recordings reveal a differential depression of synaptic transmission from primary afferents during fictive locomotion and scratch
  • Selective suppression of group II sensory input to spinal interneurons during fictive locomotion in the cat
  • Variations in the delay between the onset of hip and ankle flexors during fictive locomotion
  • Postnatal maturation of motor representation in M1
  • Transmission from group II muscle afferents in the midlumbar spinal segments is not depressed by stimulation of corticospinal fibres
  • Planning to Minimize the Human Muscular Effort during Forceful Human-Robot Collaboration
  • Heterogeneity in form and function of the rat extensor digitorum longus motor unit
  • The effect of limb position on a static knee extension task can be explained with a simple spinal cord circuit model
  • Caudal–Rostral Progression of Alpha Motoneuron Degeneration in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
  • Robust Iterative Learning Control for Pneumatic Muscle with Uncertainties and State Constraints
  • Presynaptic control of transmission through group II muscle afferents in the midlumbar and sacral segments of the spinal cord is independent of corticospinal control.
  • A Simplified Model of Motor Control
  • How do we ensure that bioelectronic devices revolutionize medicine and healthcare?
  • How do we overcome the current limitations of bioelectronic sensors used in healthcare and medicine?
  • How do we overcome the current limitations of environmental bioelectronic sensors?
  • How do we ensure safety and effectiveness of bioelectronic devices and judge when they are truly necessary for the rehabilitation of neurological conditions?
  • Simplified Markerless Stride Detection Pipeline (sMaSDP) for Surface EMG Segmentation

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