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A Deep Learning-based Integrated Framework for Quality-aware Undersampled Cine Cardiac MRI Reconstruction and Analysis
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  • Ines Machado ,
  • Esther Puyol-Antón ,
  • Kerstin Hammernik ,
  • Gastao Cruz ,
  • Devran Ugurlu ,
  • Ihsane Olakorede ,
  • Ilkay Oksuz ,
  • Bram Ruijsink ,
  • Miguel Castelo-Branco ,
  • Alistair Young ,
  • Claudia Prieto ,
  • Julia A. Schnabel ,
  • Andrew King
Ines Machado
Kings College London

Corresponding Author:[email protected]

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Esther Puyol-Antón
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Kerstin Hammernik
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Gastao Cruz
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Devran Ugurlu
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Ihsane Olakorede
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Ilkay Oksuz
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Bram Ruijsink
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Miguel Castelo-Branco
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Alistair Young
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Claudia Prieto
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Julia A. Schnabel
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Andrew King
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Abstract

Cine cardiac magnetic resonance (CMR) imaging is considered the gold standard for cardiac function evaluation. However, cine CMR acquisition is inherently slow and in recent decades considerable effort has been put into accelerating scan times without compromising image quality or the accuracy of derived results. In this paper, we present a fully-automated, quality-controlled integrated framework for reconstruction, segmentation and downstream analysis of undersampled cine CMR data. The framework enables active acquisition of radial k-space data, in which acquisition can be stopped as soon as acquired data are sufficient to produce high quality reconstructions and segmentations. This results in reduced scan times and automated analysis, enabling robust and accurate estimation of functional biomarkers. To demonstrate the feasibility of the proposed approach, we perform realistic simulations of radial k-space acquisitions on a dataset of subjects from the UK Biobank and present results on in-vivo cine CMR k-space data collected from healthy subjects. The results demonstrate that our method can produce quality-controlled images in a mean scan time reduced from 12 to 4 seconds per slice, and that image quality is sufficient to allow clinically relevant parameters to be automatically estimated to within 5% mean absolute difference.
2023Published in IEEE Transactions on Biomedical Engineering on pages 1-11. 10.1109/TBME.2023.3321431