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Design of a therapeutic ultrasound array for small volume blood-brain barrier opening in macaques
  • Thomas Manuel ,
  • M. Anthony Phipps ,
  • Charles Caskey
Thomas Manuel
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M. Anthony Phipps
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Charles Caskey
Vanderbilt University Medical Center

Corresponding Author:[email protected]

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Abstract

This work describes the design and testing of a therapeutic ultrasound array for transcranial blood brain barrier opening in macaques. The design leverages transcranial simulations to optimize for small opening volumes targetted at single brain regions. We also provide details on integrating the system into magnetic resonance image guided procedures.