Chronic diseases, such as diabetes, hypertension, and heart disease, are a growing public health concern globally. The burden of these diseases on healthcare systems and patients is enormous. To address these challenges, innovative technologies, such as chatbots, have emerged as promising solutions to improve chronic disease management. Chatbots are artificial intelligence (AI) programs that can simulate conversations with humans and provide personalized and cost-effective care. This research paper aims to explore the key use cases for chatbots in chronic disease management, such as personalized education, symptom monitoring, medication management, and lifestyle coaching. Furthermore, it discusses the potential benefits and challenges of chatbots in chronic disease management, including patient engagement, data privacy, and the need for human oversight. Finally, the paper concludes that chatbots have the potential to transform chronic disease management by providing personalized and cost-effective care, but their integration into healthcare systems requires careful consideration of ethical, legal, and regulatory frameworks.