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Cell Nucleus-Graph Convolutional Network Evaluation of Immunohistochemistry Images of Colorectal Cancer
  • +3
  • Qianghao Huang ,
  • Zhuorui Mo ,
  • Cao yuqi ,
  • Weiting Ge ,
  • Dibo Hou ,
  • Guangxin Zhang
Qianghao Huang
Zhejiang University

Corresponding Author:[email protected]

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Zhuorui Mo
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Weiting Ge
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Guangxin Zhang
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Abstract

This study proposed a method for interpreting immunohistochemistry (IHC) images based on a graph convolutional network (GCN). Self-supervised transfer learning was employed to obtain cell nucleus segmentation masks, providing effective strong cues for a cell nucleus graph (CN-G). This study applys a GCN to end-to-end diagnostic classification tasks for IHC images, fully considering global distribution features and local details in images. We believe that our study makes a significant contribution to the literature because the proposed approach ensures high accuracy in the relevant tasks while addressing the challenges of the lack of labeled datasets and high number of sample pixels.