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photoacoustic imaging with photoacoustic markers: an ex vivo demonstration
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  • Hyunwoo Song ,
  • Hamid Moradi ,
  • Baichuan Jiang ,
  • keshuai xu ,
  • Yixuan Wu ,
  • Russell Taylor ,
  • Anton Deguet ,
  • Jin U. Kang ,
  • Septimiu Salcudean ,
  • Emad M. Boctor
Hyunwoo Song
the Johns Hopkins University

Corresponding Author:[email protected]

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Hamid Moradi
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Baichuan Jiang
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keshuai xu
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Yixuan Wu
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Russell Taylor
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Anton Deguet
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Jin U. Kang
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Septimiu Salcudean
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Emad M. Boctor
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Abstract

This paper introduces an integrated real-time intraoperative surgical guidance system, in which an endoscope camera of da Vinci surgical robot and a transrectal ultrasound (TRUS) transducer are co-registered using photoacoustic markers that are detected in both fluorescence (FL) and photoacoustic (PA) imaging. The co-registered system enables the TRUS transducer to track the laser spot illuminated by a pulsed-laser-diode attached to the surgical instrument, providing both FL and PA images of the surgical region-of- interest (ROI). As a result, the generated photoacoustic marker is visualized and localized in the da Vinci endoscopic FL images, and the corresponding tracking can be conducted by rotating the TRUS transducer to display the PA image of the marker. A quantitative evaluation revealed that the average registration and tracking errors were 0.84 mm and 1.16°, respectively. This study shows that the co-registered photoacoustic marker tracking can be effectively deployed intraoperatively using TRUS+PA imaging providing functional guidance of the surgical ROI.
Mar 2023Published in IEEE Robotics and Automation Letters volume 8 issue 3 on pages 1287-1294. 10.1109/LRA.2022.3191788